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CASE REPORT Pediatric pulmonary embolism and nephrotic syndrome Raquel Costa, Susana Gomes, Rosário Stone, Rosário Ferreira
Thromboembolic complications, such as pulmonary embolism, are well-documented complications in nephrotic syndrome.
Port J Nephrol Hypert 2018; 32(2): 99-102 Advance Access publication 10 February 2018 DOWNLOAD PDF
ACKNOWLEDGEMENT OF OUR REVIEWERS A time to thank the PJNH reviewers of 2017 The Editorial Board
Peer review is the foundation of any journal, providing a trusted form of scientific communication.
Port J Nephrol Hypert 2018; 32(1): 92 Advance Access publication 22 March 2018 DOWNLOAD PDF
NEPHROPATHOLOGY QUIZ A 54-year-old man with new-onset nephrotic syndrome Bernardo Marques da Costa, Mário Góis, Helena Viana, Fernando Nolasco
A 54-year-old Caucasian airplane technician presented in outpatient evaluation with slow-onset lower extremity oedema, foamy urine and hypercholesterolemia on routine blood tests.
Port J Nephrol Hypert 2018; 32(1): 85-88 Advance Access publication 28 March 2018 DOWNLOAD PDF
REVIEW ARTICLE Diagnosis of monoclonal gammopathy of renal significance Sofia O Correia, Sofia Santos, La Salete Martins, Josefina Santos
Monoclonal gammopathies are a heterogeneous group of disorders characterized by clonal proliferation of immunoglobulin produced by B-lymphocytes or plasma cell clone.
Port J Nephrol Hypert 2018; 32(1): 52-56 Advance Access publication 28 March 2018 DOWNLOAD PDF
REVIEW ARTICLE Off-target effects and adverse outcomes of fibroblast growth factor 23 in chronic kidney disease Giovana S. Di Marco, Marcus Brand
Chronic kidney disease (CKD) patients have a high risk of death, especially cardiovascular death.
Port J Nephrol Hypert 2018; 32(1): 57-63 Advance Access publication 28 March 2018 DOWNLOAD PDF
TUBULAR QUIZ An adult patient with hypokalemia Sandra Brum, Ana Rita Santos, Catarina Silveira, Fernando Nolasco, José Rueff, Joaquim Calado
SP, a southeast Asian male born in East Timor, was 53 years old by the time he came to our attention.
Port J Nephrol Hypert 2018; 32(1): 89-91 Advance Access publication 5 April 2018 DOWNLOAD PDF
PERSPECTIVE Seven years after "Norma 17": what has changed? Ana Farinha, Ana Branco
Although huge medical advances have been made in dialysis treatments, older patients with higher comorbidities or poorer functional status may have limited survival advantage.
Port J Nephrol Hypert 2018; 32(1): 11-15 Advance Access publication 28 March 2018 DOWNLOAD PDF
EDITORIAL Fighting glomerular hegemony: giving the renal tubule the credits it deserves Joaquim Calado
This new editorial feature, the tubular quiz, aims at renewing the interest of Portuguese nephrologists in both clinical evaluation and research in renal physiology and disorders that affect the renal tubule.
Port J Nephrol Hypert 2018; 32(1): 9-10 Advance Access publication 5 April 2018 DOWNLOAD PDF
EDITORIAL A new millennium for women and kidney disease Nicole Pestana, Pedro Vieira, Gil Silva
Taking advantage of this year’s synergy, as World Kidney Day (WKD) and International Women’s Day fall on the same day, the theme chosen for WKD 2018 was “Kidneys and Women’s health”, drawing the attention of the nephrology community to the special features of diseases of the kidney as they affect women.
Port J Nephrol Hypert 2018; 32(1): 5-8 Advance Access publication 5 April 2018 DOWNLOAD PDF
CASE REPORT Light and heavy chain deposition disease - Case report João Cassis, Henrique Silva Sousa, Tiago J Carvalho, Ilídio Rodrigues, Maria Pedro Silveira
Monoclonal immunoglobulin deposition disease is part of the spectrum of monoclonal gammopathy of renal significance.
Port J Nephrol Hypert 2018; 32(2): 103-106 Advance Access publication 25 May 2018 DOWNLOAD PDF
REVIEW ARTICLE Supportive care in advanced chronic kidney disease: Comprehensive conservative care C Belino, C Meng, R Neto, E Gonçalves, M Pestana
Incident and prevalent patients on dialysis are progressively older, with high comorbidity burden and functional dependency.
Port J Nephrol Hypert 2018; 32(2): 107-116 Advance Access publication 25 May 2018 DOWNLOAD PDF
REVIEW ARTICLE The challenge of pregnancy after kidney transplantation Patrícia Cotovio
Kidney transplantation restores the impairment in fertility of end-stage renal disease patients.
Port J Nephrol Hypert 2018; 32(2): 117-122 Advance Access publication 7 June 2018 DOWNLOAD PDF
LETTER TO THE EDITOR Acute renal injury as a manifestation of Addison syndrome in a 66-year-old female patient Igor Romaniouk, Maria Araznzazu, Antonio Romero
Addison syndrome is a hormonal deficiency caused by damage to the adrenal gland which leads to hypofunction or primary adrenal insufficiency.
Port J Nephrol Hypert 2018; 32(1): 83-84 Advance Access publication 13 March 2018 DOWNLOAD PDF
ORIGINAL ARTICLE Urine volume and residual renal function decline among patients on peritoneal dialysis ? searching for associations Ricardo A. Macau, Joana R. Silva, Andreia Leite, Rita Magriço, Pedro Bravo, Fernando Teixeira e Costa, Aura Ramos
Introduction: Preservation of urine volume and residual renal function in patients on peritoneal dialysis (PD) is a major concern.
Port J Nephrol Hypert 2018; 32(1): 35-41 Advance Access publication 13 March 2018 DOWNLOAD PDF
ORIGINAL ARTICLE Color doppler ultrasound assessment of juxta-anastomotic stenosis in radiocephalic arteriovenous fistulas Ana Pimentel, Paulo Almeida, Norton de Matos, Luís Loureiro, Gabriela Teixeira, Duarte Rego, Sérgio Teixeira, Joaquim Pinheiro, Isabel Fonseca, Telmo Carvalho, José Queirós
Background: Juxta-anastomotic stenosis (JAS) is a common complication of radiocephalic arteriovenous fistulas.
Port J Nephrol Hypert 2018; 32(1): 29-34 Advance Access publication 13 March 2018 DOWNLOAD PDF
CASE REPORT Coexistence of pheochromocytoma and renal artery stenosis in a pediatric patient with hypertension Inês Serras, Rute Baeta Baptista, Telma Francisco, Anaxore Casimiro, David Lito, Rui Alves, Margarida Abranches
Pheochromocytoma and renal artery stenosis are surgically treatable causes of hypertension.
Port J Nephrol Hypert 2018; 32(1): 78-82 Advance Access publication 13 March 2018 DOWNLOAD PDF
ORIGINAL ARTICLE Tell me your weight before kidney transplant and I?ll tell you your risks Joana Silva Costa, Emanuel Ferreira, Rita Leal, Catarina Romãozinho, Lídia Santos, Fernando Macário, Rui Alves, Arnaldo Figueiredo
Introduction and aims: Overweight is highly prevalent in kidney transplant candidates and it has been associated with multiple post-transplant complications.
Port J Nephrol Hypert 2018; 32(1): 22-28 Advance Access publication 28 February 2018 DOWNLOAD PDF
ORIGINAL ARTICLE Hemodialysis arteriovenous fistula outcomes in elderly patients: a single-centre cohort Hugo Ferreira, Hugo Diniz, Patrícia Martins, Luís Coentrão
The cohort of older age pre‑dialysis patients is growing steadily. However, “Fistula First” may not always be the best strategy due to poorer arteriovenous fistula outcomes in this population.
Port J Nephrol Hypert 2018; 32(1): 16-21 Advance Access publication 14 February 2018 DOWNLOAD PDF
CASE REPORT C3 glomerulopathy: a rare kidney histological presentation of multiple myeloma Joana Silva Costa, Catarina Romãozinho, Luís Rodrigues, Carol Marinho, Vitor Sousa, Jorge Pratas, Maria Augusta Cipriano, Rui Alves
C3 Glomerulopathy is a rare disease caused by abnormal control of the alternative complement pathway, resulting in a predominant glomerular C3 deposition.
Port J Nephrol Hypert 2018; 32(1): 69-74 Advance Access publication 10 February 2018 DOWNLOAD PDF
CASE REPORT Prostate involvement in granulomatosis with polyangiitis: response to rituximab treatment David Navarro, Charles Pusey
Granulomatosis with polyangiitis is an autoimmune vasculitic condition strongly associated with anti-neutrophil cytoplasm antibodies.
Port J Nephrol Hypert 2018; 32(1): 75-77 Advance Access publication 10 February 2018 DOWNLOAD PDF
REVIEW ARTICLE Clinical implications of anti-HLA antibodies testing in kidney transplantation Jorge Malheiro, Sandra Tafulo
Alloantibodies against donor human leukocyte antigens (HLA), termed as donor‑specific antibodies (DSA), are one of the most important factors for both early and late kidney allograft dysfunction.
Port J Nephrol Hypert 2018; 32(1): 42-51 Advance Access publication 1 February 2018 DOWNLOAD PDF
CASE REPORT C3 glomerulonephritis disguised as Postinfectious GN Alice Lança, Paulo Santos, Karina Lopes, Francisco Ferrer, Ana Vila Lobos
It is not uncommon for atypical cases of postinfectious glomerulonephritis (PIGN) to be confused with C3 glomerulonephritis (C3GN) due to considerable overlap of their clinical and histopathological features.
Port J Nephrol Hypert 2018; 32(1): 64-68 Advance Access publication 1 February 2018 DOWNLOAD PDF
CASE REPORT Cortical nephrocalcinosis asymmetrically involving the kidneys: a case report documenting the development via imaging Ana Isabel Simões Ferreira, Natália Ferreira, João Leitão, José Fonseca-Santos
We report the case of a 38-year-old man with known human immunodeficiency virus infection who presented with severe Bordetella Bronchiseptica pneumoniae that led to septic shock and acute renal insufficiency, after which he developed bilateral cortical nephrocalcinosis, affecting most severely the right kidney with associated atrophy.
Port J Nephrol Hypert 2017; 31(4): 300-304 Advance Access publication 17 November 2017 DOWNLOAD PDF
MINI-REVIEW Hyperinfection syndrome with hypereosinophilia and chronic kidney disease: case report and review Noélia Lopez, Alice Fortes, Estela Nogueira, Iolanda Godinho, Sofia Jorge, Tiago Marques, Paulo Fernandes, António G Costa
Chronic kidney disease (CKD) is associated to significant infection incidence and severity, the cause of death of, approximately, 20% of end-stage renal disease patients.
Port J Nephrol Hypert 2017; 31(4): 249-253 Advance Access publication 17 November 2017 DOWNLOAD PDF
ORIGINAL ARTICLE Factors associated with early fistula failure: how to improve it C. Belino, S. Pereira, A. Ventura, V. Martins, C. Nogueira, JC. Fernandes
Introduction: Around the world, risk factors for fistula failure have been considered in vascular access planning in order to improve results. However, primary fistula failure rates seem to be increasing. 
Port J Nephrol Hypert 2017; 31(4): 262-267 Advance Access publication 17 November 2017 DOWNLOAD PDF
MINI REVIEW IgG4-tubulointerstitial nephritis: a literature review following 5 cases in a single centre Joana Rocha, Amy Kang, Nikki Wong, Joseph Westaby, Candice Roufosse, Terence Cook
Immunoglobulin G4‑related disease is a recently described systemic fibro‑inflammatory disease, characterized by an infiltration of abundant IgG4+ plasma cells and lymphocytes, leading to tumour‑like swellings of the involved organs, and variable degrees of fibrosis.
Port J Nephrol Hypert 2017; 31(4): 254-261 Advance Access publication 11 December 2017 DOWNLOAD PDF
ORIGINAL ARTICLE Predicting early mortality in incident hemodialysis patients: strengthening a shared decision-making process Carolina L. Belino, Augusto M. Coelho, Susana J. Pereira, Daniela M. Lopes, C. Silva, Ana M. Gomes, Ana M. Ventura
Introduction: The benefits of dialysis in the elderly are dubious. A shared decision‑making process, helped by adequate prognostic tools, is essential to determine which patients are better candidates for conservative care.
Port J Nephrol Hypert 2017; 31(4): 268-273 Advance Access publication 11 December 2017 DOWNLOAD PDF
ORIGINAL ARTICLE Are we building too many arteriovenous fistulas? A single-center experience Carla Leal Moreira, Vanda Teixeira, Lígia Bessa, José Queirós, Fernanda Silva, António Cabrita
Introduction: Arteriovenous fistula has been associated with improved morbimortality in hemodialysis patients.This has resulted in the “fistula First, catheter last” initiative. Nonetheless, the survival benefit of arteriovenous fistula has been questioned.
Port J Nephrol Hypert 2017; 31(4): 274-280 Advance Access publication 19 December 2017 DOWNLOAD PDF
LETTER TO THE EDITOR Open data on kidney transplantation Nuno Moreira Fonseca
To the Editor,In his recent article “A call for open data of renal transplantation in Portugal” Lima calls for free, accessible, and disaggregated data on kidney transplantation.While I fully support this request, I must take issue with the stakeholders it addresses.
Port J Nephrol Hypert 2017; 31(4): 321 Advance Access publication 21 December 2017 DOWNLOAD PDF
PERSPECTIVE Kidney biopsy in Lupus Nephritis: still essential in clinical practice Fernando Pereira, Liliana Cunha, Rita Manso, Karina Soto, Brad H Rovin
Renal involvement in Systemic Lupus Erythematous is common and its management remains a daily challenge for clinical providers.
Port J Nephrol Hypert 2017; 31(4): 237-242 Advance Access publication 21 December 2017 DOWNLOAD PDF
COMMENT Vascular access unsolved problem - When, which and for whom? Maria Guedes Marques, Pedro Maia
I congratulate the authors on their recent analysis of the dilemma regarding the timing and type of vascular access creation1-3.
Port J Nephrol Hypert 2017; 31(4): 283-285 Advance Access publication 28 December 2017 DOWNLOAD PDF
CASE REPORT 72-year-old man with acute kidney injury, hypercalcemia and metastatic prostate cancer Alice Lança, Paulo Santos, Francisco Ferrer
Paraproteinemias are characterized by the abnormal expansion of a plasma cell clone with overproduction of a monoclonal (M) immunoglobulin.
Port J Nephrol Hypert 2017; 31(4): 310-314 Advance Access publication 17 November 2017 DOWNLOAD PDF
CASE REPORT Crescentic IgA nephropathy with preserved renal function Ricardo A. Macau, Joana R. Silva, Hélder Coelho, Pedro Bravo, Fernanda Carvalho, Aura Ramos
Crescentic glomerulonephritis is a severe form of glomerular inflammation. IgA nephropathy (IgAN) is the most common primary glomerulonephritis and rarely presents as crescentic glomerulonephritis with rapidly progressive glomerulonephritis.
Port J Nephrol Hypert 2017; 31(4): 315-320 Advance Access publication 2 January 2018 DOWNLOAD PDF
NEPHROPATHOLOGY QUIZ Acute allograft dysfunction: a case hanging by a thread Marta Sofia Costa, Sofia Coelho, Ivo Laranjinha, Mário Góis, Helena Viana, Fernando Nolasco
A 49-year-old man with end-stage renal disease secondary to ANCA-MPO vasculitis received a deceased-donor allograft kidney with two mismatches.
Port J Nephrol Hypert 2017; 31(4): 322-325 Advance Access publication 3 January 2018 DOWNLOAD PDF
PERSPECTIVE Is tolvaptan a promising ally in the treatment strategy of autosomal dominant polycystic kidney disease? Sara Fernandes, Catarina Teixeira, Luís Falcão, Ana Cortesão Costa, Edgar A F de Almeida
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is one of the most common monogenic diseases in humans.
Port J Nephrol Hypert 2017; 31(4): 243-248 Advance Access publication 4 January 2018 DOWNLOAD PDF
REVIEW ARTICLE Lecithin-cholesterol acyltransferase deficiency: a review for clinical nephrologists Rute Carmo, I. Castro-Ferreira, João Paulo Oliveira
Lecithin-cholesterol acyltransferase (LCAT) is the enzyme responsible for esterification of free cholesterol on the surface of lipoproteins, particularly in high-density lipoproteins (HDL), and is also involved in the reverse transport of cholesterol from peripheral tissues to the liver.
Port J Nephrol Hypert 2017; 31(4): 286-292 Advance Access publication 3 January 2018 DOWNLOAD PDF
REVIEW ARTICLE The role of bone biomarkers and new imaging techniques in the management of patients with CKD-MBD C Belino, C Meng, L Pereira, C Carvalho, R Neto
Chronic kidney Disease – Mineral and Bone Disorder (CKD-MBD) encompasses abnormalities in bone turnover, volume and mineralization, compromising bone quantity and quality.
Port J Nephrol Hypert 2017; 31(4): 293-299 Advance Access publication 2 January 2018 DOWNLOAD PDF
REVIEW ARTICLE Are there benefits of a high potassium diet, even in the CKD patient? Biff F. Palmer, Deborah J. Clegg
Recent data have demonstrated dietary intake of potassium (K+) is well below current recommended nutritional guidelines, and K+ deficiency has been implicated in many diseases to include cardiovascular disease, kidney stones, and osteoporosis.
Port J Nephrol Hypert 2017; 31(2): 115-121 Advance Access publication 11 May 2017 DOWNLOAD PDF
EDITORIAL Anion gap metabolic acidosis Biff F. Palmer, Deborah J. Clegg
Metabolic acidosis is defined as a low arterial blood pH in conjunction with a reduced serum HCO3- concentration.
Port J Nephrol Hypert 2017; 31(2): 73-78 Advance Access publication 12 June 2017 DOWNLOAD PDF
REVIEW ARTICLE Dialysis catheter malfunction Maria G Marques, Pedro Maia, Pedro Ponce
Vascular access is a crucial factor in the treatment of hemodialysis patients. Dialysis catheters are associated with higher mortality than fistulas, meaning they should be the last choice for most patients. Although they have many drawbacks, catheters play an important role in providing a reliable vascular access in some patients.
Port J Nephrol Hypert 2017; 31(3): 184-191 Advance Access publication 6 September 2017 DOWNLOAD PDF
REVIEW ARTICLE Symptom control in End Stage Renal Disease Ana Farinha
Chronic kidney disease (CKD) patients experience a high burden of symptoms that are not always recognized or relieved by standard measures.
Port J Nephrol Hypert 2017; 31(3): 192-199 Advance Access publication 18 September 2017 DOWNLOAD PDF
PERSPECTIVE Tips for publishing an original article Ana Carina Ferreira, Pedro Escada
Writing an article is a goal for not only many researchers, but also for many clinicians.
Port J Nephrol Hypert 2017; 31(3): 158-161 Advance Access publication 2 October 2017 DOWNLOAD PDF
REVIEW ARTICLE Glucosylceramides and kidney disease Alberto Ortiz, Maria Dolores Sanchez?Niño
Glucosylceramides are part of the wider family of glycosylceramides. Glucosylceramide synthase catalyzes the incorporation of a single glucose residue into ceramide to yield glucosylceramide.
Port J Nephrol Hypert 2017; 31(3): 200-206 Advance Access publication 3 October 2017 DOWNLOAD PDF
ORIGINAL ARTICLE Diagnosis and treatment of haemodialysis vascular access problems without iodinated contrast: A single-centre experience Joana Francisca Rocha, Mónica Fructuoso, Pedro Filipe Sousa, Joana Ferreira, Rui Miguel Abreu, Catarina Eusébio, Teresa Morgado
Introduction: The use of iodinated contrast angiography in the diagnostic and therapeutic approach to arteriovenous access (AVA) problems is limited by nephrotoxicity and allergic reactions.
Port J Nephrol Hypert 2017; 31(3): 175-182 Advance Access publication 3 October 2017 DOWNLOAD PDF
ORIGINAL ARTICLE Echocardiography and cardiovascular risk: The relationship in the renal transplant recipient Miguel Gonçalves, Micaela Neto, Nicole Pestana, Luís Resende, Pedro Vieira, Susana Gomes, José Durães, Nuno Rosa, José Alves Teixeira, Gil Silva
Introduction: Cardiovascular disease (CVD) is the major cause of death among renal transplant recipients (RTR).
Port J Nephrol Hypert 2017; 31(3): 167-174 Advance Access publication 3 October 2017 DOWNLOAD PDF
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